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| Product Name | Bcl 2, aa1-211, Recombinant, Human |
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| Description | Highly Purified (~90%). Bcl-2, also known as B-cell lymphoma protein 2 alpha, is an anti-apoptotic protein located primarily in the outer mitochondrial membrane that blocks the apoptotic death of some cells such as lymphocytes. BCL-2 is thought to regulate cell death by controlling the mitochondrial membrane permeability during apotosis. Bcl-2 exerts its anti-apoptotic function through inhibiting caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). The Bcl-2 gene has been related with a number of cancers, including melanoma, breast, prostate, and lung carcinomas, as well as schizophrenia and autoimmunity. Source: Recombinant protein corresponding to human Bcl2, aa1-211, with C-terminal His-Tag, expressed in E. coli. Molecular Weight: ~27kD Applications: Suitable for use in the study of apoptosis, screening inhibitors, and selectivity profiling. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Bcl 2, aa1-211, Recombinant, Human (B Cell lymphoma protein 2 alpha, Apoptosis regulator Bcl-2, Bcl-2) |
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| Gene, Accession, CAS # | SwissProt: P10415 |
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| Catalog # | B0807-02F1 |
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| Order / More Info | Bcl 2, aa1-211, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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