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| Product Name | BPIFA1, Recombinant, Human, aa20-256, His-SUMO-Tag (BPI fold-containing Family A Member 1) |
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| Description | Purity ~90% (SDS-PAGE). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Binds bacterial lipopolysaccharide (LPS). Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants. May attract macrophages and neutrophils. May be associated with tumor progression. Source: Recombinant protein corresponding to aa20-256 from human BPIFA1, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~40.7kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Lung-specific protein X Nasopharyngeal carcinoma-related protein, Palate lung and nasal epithelium clone protein, Secretory protein in upper respiratory tracts, PLUNC1, SPLUNC1, Tracheal epithelium-enriched protein Von Ebner protein Hl |
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| Gene, Accession, CAS # | SwissProt: Q9NP55 |
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| Catalog # | 372482 |
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| Order / More Info | BPIFA1, Recombinant, Human, aa20-256, His-SUMO-Tag (BPI fold-containing Family A Member 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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