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| Product Name | CFB-Bb, 260-764aa, Human, His tag, E.coli (Denatured) |
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| Description | Purity: > 85% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol. CFB encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. Recombinant human CFB-Bb protein, fused to His-tag at N-terminus, was expressed in E.coli . |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | complement factor B, AHuS4, BF, BFD, CFAB, FB, FBI12, GBG, H2-Bf, PBF2 |
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| Gene, Accession, CAS # | NP 001701 |
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| Catalog # | ATGP2479 |
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| Order / More Info | CFB-Bb, 260-764aa, Human, His tag, E.coli (Denatured) from ATGen |
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| Product Specific References | n/a |
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