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| Product Name | Caspase, Cleaved BioAssay™ Sample Kit |
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| Description | Purified by Protein A and peptide affinity chromatography. Check status of cleaved caspase, including cleaved caspase-3 (Asp175), caspase-6 (Asp162), caspase-7 (Asp198), caspase-8 (Asp384) monoclonal, caspase-9 (Asp315) and (Asp330) (human specific). The kit contains enough primary and secondary antibodies to perform two Western mini-blot experiments with each primary antibody. Apoptosis, or programmed cell death, is a regulated physiological process leading to cell death. Caspases, a family of cysteine acid proteases, are central regulators of apoptosis. Initiator caspases (including 8, 9, 10 and 12) are closely coupled to proapoptotic signals. Once activated, these caspases cleave and activate downstream effector caspases (including 3, 6 and 7), which in turn cleave cytoskeletal and nuclear proteins like PARP, a-Fodrin, DFF and Lamin A, and induce apoptosis. Cytochrome c released from mitochondria is coupled to the activation of caspase-9, a key initiator caspase. Proapoptotic stimul |
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| Size | 6x20ul |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C2087-06 |
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| Order / More Info | Caspase, Cleaved BioAssay™ Sample Kit from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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