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| Product Name | IL-13 (113 a.a.), Recombinant, Rat (NC300 (Human) P600 (Murine)) |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells.Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites.IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha, IL-6 and IL-8.IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE.Blocking of IL-13 activity inhibits the pathophysiology of asthma.Human and murine IL-13 is cross-species reactive.Recombinant rat IL-13 is a 12.3kD protein consisting of 113 amino acid residues. Biological Activity: The ED50 was determined by the dose-dependent proliferation of TF-1 cells is ≤5.0ng/ml, corresponding to a specific activity of ≥2x10e5 units/mg. Amino Ac |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143384 |
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| Order / More Info | IL-13 (113 a.a.), Recombinant, Rat (NC300 (Human) P600 (Murine)) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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