产品名称 Oxyphenbutazone from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H9229
产品价格 现货询价,电话:010-67529703
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产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NameOxyphenbutazone
DescriptionPurity >98%. Oxyphenbutazone is a metabolite of phenylbutazone . Both compounds were identified as having anti-inflammatory effects in early studies, and, as a result, are considered NSAIDs. Interestingly, the effects of the two compounds in animal models differ, with phenylbutazone having anti-inflammatory effects in rheumatic diseases and oxyphenbutazone reducing edema in certain types of acute inflammation. Oxyphenbutazone is a poor inhibitor of prostaglandin synthesis, but, like other NSAIDs, it inhibits organic anion transporter 1 (Ki = 32 µM). It inhibits the growth of MH60/BSF-2 cells induced by IL-6 (IC50 = 7.5 µM). Oxyphenbutazone stimulates neurite outgrowth at 1.5 µM and sensitizes M. tuberculosis to antimicrobials.
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Other Names4-butyl-1-(4-hydroxyphenyl)-2-phenyl-3,5-pyrazolidinedione, G 27202, NSC 526053, p-Hydroxyphenylbutazone, Ro 04-4410
Gene, Accession, CAS #CAS: 129-20-4
Catalog #LS-H9229
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Order / More InfoOxyphenbutazone from LIFESPAN BIOSCIENCES INC.
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