| 产品详情 |
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| Product Name | Akt Inhibitor, Isozyme-Selective |
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| Description | Purity >97 % by HPLC. Cell-permeable. A potent and selective inhibitor of Akt1/Akt2 activity (IC50 = 58 nM (Akt1), 210 nM (Akt2) and 2.12 µM (Akt3) in in vitro kinase assays). The inhibition appears to be pleckstrin homology (PH) domain-dependent. It does not exhibit any inhibitory effect against PH domain-lacking Akts, or other closely related AGC family kinases, PKA, PKC, and SGK, even at concentrations (50 µM). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one, Akti-1/2 |
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| Gene, Accession, CAS # | CAS: 612847-09-3 |
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| Catalog # | LS-H2413 |
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| Order / More Info | Akt Inhibitor, Isozyme-Selective from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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