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| Product Name | Akt Inhibitor (10-NCP) |
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| Description | MW: 381.34. Purity ≥98% by HPLC. Background: Cell-permeable. A reversible and specific inhibitor of Akt activity in vitro (complete inhibition at < 5 uM). Displays minimal effect on PI 3-K, PDK1, or SGK1. Blocks IGF-I stimulated nuclear translocation of Akt in Rh1 cells and suppressed growth of Rh1, Rh18, and Rh30 cells (IC?? = 2-5 uM). Also shown to induce neuronal autophagy in an Akt- and mTOR-independent manner and enhances the clearance of misfolded protein. |
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| Size | 1 mg, 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [10-(4?-(N-diethylamino)butyl)-2-chlorophenoxazine hydrochloride] |
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| Gene, Accession, CAS # | CAS: 925681-41-0 |
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| Catalog # | MBS843042 |
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| Order / More Info | Akt Inhibitor (10-NCP) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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