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| Product Name | BRPF3, Recombinant, Human, aa576-701, GST-tag |
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| Description | Purity ~95% (SDS-PAGE). The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as ``readers'' of histone acetylation marks regulating the transcription of target promoters. Bromodomain and PHD finger containing 3 (BRPF3) is a component of the MOZ/MORF histone acetyltransferase (HAT) complex. The addition of BRPF proteins to MOZ/MORF increases its HAT activity. Consequently, BRPF3 is likely to play a role in regulation of transcriptional activation by MOZ/MORF. This product contains the first bromodomain of BRPF3. Source: Recombinant pro |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BRPF3, Recombinant, Human, aa576-701, GST-tag (Bromodomain and PHD Finger Containing 3, KIAA1286, MGC:58603) |
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| Gene, Accession, CAS # | BRPF3, Gene ID: 6872, SwissProt: Q9ULD4 |
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| Catalog # | 219508 |
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| Order / More Info | BRPF3, Recombinant, Human, aa576-701, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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