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| Product Name | Complement C5a, Recombinant, Mouse, His-Tag |
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| Description | Purity ~95% (SDS-PAGE). Mouse complement C5a is a 77aa peptide generated during complement activation from the alpha-chain of complement C5. C5a binds to a signaling G-protein coupled receptor (GPCR) (C5aR/CD88), inducing neutrophil chemotaxis and endothelial cell activation. It also triggers an oxidative burst in macrophages and neutrophils, and induces release of histamine in basophils and mast cells. Source: Recombinant protein corresponding to mouse Complement C5a, fused to His-tag at N-terminal, expressed in E. coli. Molecular Weight: ~9kD Biological Activity: The ED50 is 1-3nM, as determined by enzyme release assay of myeloperoxidase Endotoxin: <0.1ng/ug Specificity: Mouse C5a shares 60% and 82% aa sequence identity to human and rat C5a, respectively. |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Complement C5a, Recombinant, Mouse, His-Tag (C5a, Complement Component 5a, Complement Fragment C5a, Complement-Derived C5a, Complement C5a Protein) |
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| Gene, Accession, CAS # | C5a, Gene ID: 15139, Accession: NP_034536 |
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| Catalog # | 219665 |
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| Order / More Info | Complement C5a, Recombinant, Mouse, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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