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| Product Name | Active Recombinant human Growth Hormone |
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| Description | Human recombinant protein expressed in Nicotiana benthamiana. It is produced by transient expression in non-transgenic plants. This product contains no animal-derived components or impurities. Animal Free product. GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. Recombinant human GH is a protein composed of 22.9 kDa, 205 amino residues. Purity >97% by SDS-PAGE gel |
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| Size | 1 µg, 10 µg, 50µg, 100µg, 1000µg |
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| Concentration | n/a |
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| Applications | Functional studies, Cell culture, Western Blot, Dermocosmetics (rh GH stimulates fibroblast cell proliferation, kerotinocytes migration (HaCaT cells) and induces whitening activity ). |
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| Other Names | Somatotropin; Growth hormone 1; Pituitary growth hormone |
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| Gene, Accession, CAS # | UniProt: P01241 |
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| Catalog # | RF0011 |
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| Order / More Info | Active Recombinant human Growth Hormone from AGRENVEC |
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| Product Specific References | - Chen, H.C. et al. J. Biol. Chem. 245, 3402-3406 (1970) - Goffin, V. et al., Endocrine Rev. 17, 385-410 (1996) - Le Roith, D. et al. Endocrine Rev. 22, 53-74 (2001) - Roskam, W. et al. Nucleic Acids res. 7, 305-320 (1979) - Welniak, L.A. et al. J. Leukoc. Biol. 71, 381-387 (2002) |
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