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| Product Name | Active Recombinant Human Interferon alpha-2a |
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| Description | Human recombinant protein expressed in Nicotiana benthamiana. It is produced by transient expression in non-transgenic plants. This product contains no animal-derived components or impurities. Animal Free product. Interferon alpha 2a is an interferon class I produced by the cells of the innate immune system as a part of the defense response to foreign agents such as viruses, parasites and tumour cells. The human alpha-interferon family displays broad spectrum antiviral, antiproliferative and immunomodulatory activities on a variety of cell types. Interferon Alpha-2a (IFNa-2a), one of the subtypes, is a protein consisting of 165 amino acid. Its three-dimensional loop structure is maintained by two disulphide bridges. It has an approximate molecular weight of 20 kDa. Recombinant human IFN-alpha-2a is a polypeptide single chain containing 171 amino acids with a predicted molecular mass of 20.1 kDa. Recombinant human IFN-alpha-2 contains a His-tag at the C-terminal end. Purity >97% by SDS-PAGE gel |
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| Size | 1 µg, 10 µg, 50 µg, 100 µg |
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| Concentration | n/a |
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| Applications | Functional studies, Cell culture, Western Blot. |
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| Other Names | IFN-alphaA, IFNA, INFA2, Type I interferon |
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| Gene, Accession, CAS # | UniProt: P01563 |
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| Catalog # | RF008 |
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| Order / More Info | Active Recombinant Human Interferon alpha-2a from AGRENVEC |
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| Product Specific References | - Sehgal, P. B. et al., 1981. Heterogeneity of human a and,B species, p. 43-46. In E. De Maeyer, G. Galasso, and H. Schekellens (ed.) The biology of the interferon system. Elsevier-North Holland Biochemical Press, Amsterdam. - Allen, G. and K. H. Fantes, 1980. A family of structural genes for human lymphoblastic (leukocyte type) interferon. Nature (London), 287: 408-41. - Nagata, S. et al., 1980. Synthesis in E. coli of a polypeptide with human leukocyte interferon activity. Nature (London), 284: 316-320. |
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