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| Product Name | Active Recombinant Human TGF beta-3 |
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| Description | Human recombinant protein expressed in Nicotiana benthamiana. It is produced by transient expression in non-transgenic plants. This product contains no animal-derived components or impurities. Animal Free product. Recombinant human TGF-beta3 is a 27.2 kDa protein composed of two identical 118 amino acid peptide chains linked by a single disulphide bond. Transforming growth factor-beta is a family of five related cytokines that have been shown on a wide variety of normal and neoplastic cells, indicating the importance of these homo-dimmer proteins as multi-functional regulators of cellular activity. The three mammalian isoforms of TGF-beta (TGF-beta1, TGF-beta2 and TGF-beta3) signal through the same receptor and elicit similar biological responses. They are involved in physiological processes as embryogenesis, tissue remodeling and wound healing. Recombinant human TGF-beta3 is a 27.2 kDa protein composed of two identical 118 amino acid polypeptide chains linked by a single disulphide bond. Purity >97% by SDS-PAGE gel |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Functional studies, Cell culture, Western Blot. |
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| Other Names | Transforming growth factor beta-3; TGF-beta-3 |
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| Gene, Accession, CAS # | UniProt: P10600 |
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| Catalog # | RF004 |
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| Order / More Info | Active Recombinant Human TGF beta-3 from AGRENVEC |
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| Product Specific References | -Ten Dijke, P., et al. (1988). Identification of a new member of the transforming growth factor type beta gene family. Proc. Natl. Acad. Sci. USA, 85: 4715-4719. -Massage, J. (1990). The transforming growth factor-beta family. Ann. Rev. Cell Biol., 6: 597-641. -Miller, D.A., et al. (1990). Transforming growth factor beta: a family of growth regulatory peptides. Ann. N.Y. Acad. Sci., 593: 208-217. -Bocharov. E.C., et al. (2002). Dynamics-modulated biological activity of transforming growth factor beta3 J. Biol. Chem., 277(48): 46273-46279. -Zhongcheng, Z., Sun, P.D., (2006). An improved recombinant mammalian cell expression system for human transforming growth factor-beta2 and factor-beta3 preparations. Protein Expr. Purif., 50: 9-17 |
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