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| Product Name | Ply, Recombinant, Streptococcus Pneumoniae, aa2-471, His-SUMO-Tag (Serotype 4 Pneumolysin) |
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| Description | Purity ~90% (SDS-PAGE). Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation. Source: Recombinant protein corresponding to 2-471 from streptococcus pneumoniae ply, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~68.8kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Thiol-activated cytolysin |
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| Gene, Accession, CAS # | SwissProt: P0C2J9 |
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| Catalog # | 374761 |
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| Order / More Info | Ply, Recombinant, Streptococcus Pneumoniae, aa2-471, His-SUMO-Tag (Serotype 4 Pneumolysin) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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