| 产品详情 |
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| Product Name | PMA |
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| Description | Purity >98% by HPLC. Most commonly-used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor promoter. Promoter of inducible NOS (iNOS; NOS II). Apoptosis inducer. Potential effective cancer therapeutic agent. Inhibitor of anti-lipolytic activity of insulin. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 12-O-Tetradecanoylphorbol 13-acetate, PMA, TPA |
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| Gene, Accession, CAS # | CAS: 16561-29-8 |
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| Catalog # | LS-H312 |
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| Price | |
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| Order / More Info | PMA from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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