| 产品详情 |
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| Antigenic Specificity | NQO1 |
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| Clone | A180 |
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| Host Species | Mouse |
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| Reactive Species | rat, human |
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| Isotype | IgG1 |
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| Format | Protein G purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC, IHC-P, IP, WB (1:100 - 1:1000) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NQO1 Antibody (clone A180) LS-C188428. Recognizes human NQO1 (NAD(P)H: quinone oxidoreductase 1), a 31kD cytosolic flavoenzyme and member of the NAD(P)H dehydrogenase (quinone) family, involved in detoxification, which catalyzes the two-electron reduction of quinones to hydroquinones. NQO1 is expressed in a wide range of tissues and is overexpressed in many human tumors including lung, brain, liver, colon and breast. The ability of NQO1 to bioactivate anti-tumor quinones including mitomycin C and diaziquone, has become a focus area for chemotherapeutic studies. Mutations in the NQO1 gene are associated with an increased risk of certain cancers, and an increased risk of leukaemia has been associated with diminished NQO1 activity and the NQO1 *2 allele. Clone A180 detects endogenous levels of total NQO1, and does not cross-react with NQO2. Clone A180 is reported as suitable for use in immunofluorescence studies. Does not react with: Mouse |
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| Immunogen | Purified recombinant human NQO1. |
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| Other Names | NQO1, Azoreductase, DHQU, DT-diaphorase, Dioxin-inducible 1, DIA4, Diaphorase-4, NAD(P)H:quinone oxireductase, Phylloquinone reductase, QR1, Menadione reductase, NMOR1, NMORI, DTD, Quinone reductase 1 |
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| Gene, Accession # | NQO1, Gene ID: 1728 |
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| Catalog # | LS-C188428 |
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| Price | |
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| Order / More Info | NQO1 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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