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Antigenic Specificity | Human TAB2 |
Clone | H.299.0 |
Host Species | Rabbit |
Reactive Species | human, mouse, nonhuman primate, rat |
Isotype | IgG |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit Anti-Human TAB2 monoclonal antibody for IP, WB. The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. |
Immunogen | Synthetic peptide |
Other Names | n/a |
Gene, Accession # | Gene ID: 23118, UniProt: Q9NYJ8 |
Catalog # | CABT-L1461 |
Price | |
Order / More Info | Human TAB2 Antibody from CREATIVE DIAGNOSTICS |
Product Specific References | n/a |
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