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| Product Name | Sphingomyelinase, Activity Colorimetric BioAssay™ Kit (SMase) |
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| Description | Sphingomyelinase (SMase) cleaves sphingomyelin to produce phosphocholine and ceramide. The activation of SMase leads to increased production of ceramide, which acts as a lipid second messenger that induces a variety of cell regulatory phenomena such as apoptosis, cell differentiation, cell proliferation, and sterol homeostasis. There are five distinct types of SMases. Sample Type: Animal tissues: brain, heart, kidney, etc. Cell culture: Adherent or suspension cells. Intended Use: For use in the measurement of SMase activity in various tissues/cells extracts and screening of SMase inhibitors. Sensitivity: This high-throughput adaptable assay kit can detect sphingomyelinase activity as low as 1.25mU/ml (~5 uU/mg tissue/cells) in a variety of samples. Test Principle: The SMase Activity BioAssay™ Kit provides a simple and sensitive method for measuring neutral-SMase enzymatic activity using colorimetry (OD 570nm). Neutral sphingomyelinase (N-SMase) is a Mg2+ sensitive enzyme that can |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 220277 |
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| Order / More Info | Sphingomyelinase, Activity Colorimetric BioAssay™ Kit (SMase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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