产品名称 Dihydroeponemycin from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H7455
产品价格 现货询价,电话:010-67529703
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产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NameDihydroeponemycin
DescriptionPurity >98%. Dihydroeponemycin is a natural, irreversible inhibitor of proteasomal degradation of proteins that acts by binding the IFN-Gamma-inducible proteins LMP2 and LMP7, as well as the constitutive proteasome subunit X. It potently inhibits both the chymotrypsin-like and PGPH activity, with 10-fold less inhibition of trypsin-like activity. Dihydroeponemycin does not inhibit calpain or trypsin and has minor effects on cathepsin B and chymotrypsin at higher concentrations. It is cell-permeable and induces apoptosis in bovine aortic endothelial cells.
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Other NamesN-[(1S)-1-(hydroxymethyl)-2-[[(1S)-1-[[(2R)-2-(hydroxymethyl)-2-oxiranyl]carbonyl]-3-methylbutyl]amino]-2-oxoethyl]-6-methyl-heptanamide
Gene, Accession, CAS #CAS: 126463-64-7
Catalog #LS-H7455
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Order / More InfoDihydroeponemycin from LIFESPAN BIOSCIENCES INC.
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