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| Product Name | HCC-1, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). Hemofiltrate C-C chemokine (HCC)-1 is a recently described monocyte chemoattractant. CCL14 (also known as HCC-1) belongs to the CC chemokine family. Its mature propeptide is a low-affinity agonist of CCR1 that is converted to a high-affinity agonist of CCR1 and CCR5 on proteolytic processing by serine proteases. Determination of the amino acid sequence of HCC-1 revealed four cysteine residues in positions characteristic of the C-C chemokine family, and comparison with the sequences of other chemokines revealed that HCC-1 was most homologous to MIP-1a. However, several functional properties of HCC-1 were atypical of chemokines. Unlike other chemokines, HCC-1 was expressed constitutively in a number of tissues and was present at high concentrations in normal human plasma. In addition, HCC-1 was reported not to be chemotactic for leukocytes. Source: Recombinant protein corresponding to human HCC-1 expressed in E. coli. Molecular Weight: ~9kD Biological Activity: Determined by its ability |
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| Size | 10ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HCC-1, Recombinant, Human (C-C Motif Chemokine 14, Chemokine CC-1, HCC1, HCC-3, HCC-1(1-74), NCC-2, Small-Inducible Cytokine A14, CCL14, NCC2, SCYA14) |
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| Gene, Accession, CAS # | SwissProt: Q16627 |
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| Catalog # | 500060 |
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| Order / More Info | HCC-1, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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