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| Product Name | HCC-2, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). CCL15 is a human chemokine which acts predominantly on chemokine receptor CCR1 and to a lesser degree on CCR3. It is a potent chemoattractant for monocytes and lymphocytes in vitro and, after i.p. application, CCL15 induces recruitment neutrophils, monocytes, and lymphocytes into mouse peritoneum. CCL15 is constitutively expressed in the gut and in the liver and was identified to circulate in human plasma. The N-terminal of CCL15 was found to be important to exert its full biological activity. HCC-2 shares significant sequence homology with CKb8 and the murine chemokines C10, CCF18/MRP-2, and macrophage inflammatory protein 1gamma, which all contain six instead of four conserved cysteines. Source: Recombinant protein corresponding to human HCC-2 expressed in E. coli. Molecular Weight: ~10kD Biological Activity: The ED50 was determined by the dose-dependent proliferation of human umbilical vein endothelial cells and was <0.05ng/mL. Endotoxin: <1EU/ug (LAL) |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HCC-2, Recombinant, Human (Macrophage Inflammatory Protein-5, MIP-5, HCC2, Chemokine CC-2, CCL15, Leukotactin-1, Lkn-1, MIP-1 Delta, Mrp-2b, NCC-3, Small-Inducible Cytokine A15, MIP5, NCC3, SCYA15) |
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| Gene, Accession, CAS # | SwissProt: Q16663 |
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| Catalog # | 500061 |
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| Order / More Info | HCC-2, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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