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| Product Name | CD200R1, Fc Chimera, Recombinant, Mouse (OX2R, OX2 Receptor) |
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| Description | Purity ≥ 85%, as determined by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin: ≤ 1EU/1ug. CD200 R1, also known as OX-2 receptor, is a 90kD, type I transmembrane protein that belongs to the immunoglobulin superfamily. CD200 R1 is important in the regulation of myeloid cell activity.1-3 The mouse CD200 R1 cDNA encodes a 326 aa precursor that includes a 25 aa signal sequence, a 213 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a 67 aa cytoplasmic domain. The ECD is composed of one Ig-like V-type domain and one Ig-like C2-type domain.4 Within the ECD, mouse CD200 R1 shares 56% and 70% aa sequence identity with human and rat CD200 R1, respectively. The ECD of mouse CD200 R1 shares 69%, 38%, 79%, and 83% aa sequence identity with the ECD of CD200 R2, 3, 4, and a CD200 R-like molecule, respectively. CD200 R1 is expressed primarily on mast cells, basophils, macrophages, and dendritic cells, 5-7 while its ligand, CD200, is widely distributed.8 D |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C2548-96W11 |
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| Order / More Info | CD200R1, Fc Chimera, Recombinant, Mouse (OX2R, OX2 Receptor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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