| 产品详情 |
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| Product Name | Mannosylceramide, alpha |
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| Description | Purity ~95% (TLC). Potent stimulator of natural killer T (NKT) cells expressing the invariant Valpha19-Jalpha26 T cell receptor alpha chain (Valpha19 NKT cells). Natural killer T cells (NKT cells) are important regulators of the immune system. They share properties of both innate as well as adaptive immunity. They express T cell receptors (TCR) on their surface consisting of an invariable alpha-chain and a somewhat variable beta-chain. The majority of NKT cells express the invariable alpha-chain Valpha14-Jalpha18 (Valpha14) in mouse or its homolog in humans Valpha24-Jalpha18 (Va24). Valpha14 NKT cells recognize alpha-GalCer presented by CD1d. NKT cells expressing the invariant Valpha19-Jalpha26 TCR alpha-chain (Valpha19 NKT cells) have been found in peripheral blood lymphocytes and in the liver. They recognize alpha-ManCer presented by MR1 (Major histocompatibility complex, class I-related) and respond with production of large amounts of immunoregulatory cytokines. Formula: C50H99NO9 S |
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| Size | 250ug, 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Mannosylceramide, alpha (alpha-ManCer, alpha-Mannosyl Ceramide, (2S,3S,4R)-2-Amino-N-hexacosanoyl-1-O-(alpha-D-mannopyranosyl)-1,3,4-octadecanetriol) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 207272 |
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| Price | |
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| Order / More Info | Mannosylceramide, alpha from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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