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| Product Name | FGF-10, Recombinant, Rat, aa37-215 (KGF-2, Fibroblast Growth Factor) |
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| Description | Purity ~95% (SDSPAGE). The Fibroblast Growth Factors (FGFs) are heparin binding glycoproteins that exert a variety of biological activities toward cells of mesenchymal, neuronal, and epithelial origin. FGF10 belongs to the subgroup of FGFs that also includes FGF3, 7, and 22 (1). Mature rat FGF10 is an ~20kD protein that contains a serinerich region near its Nterminus (2). It shares 96% and 91% amino acid sequence identity with human and mouse FGF10, respectively. FGF10 is secreted by mesenchymal cells and associates with extracellular FGFBP (1, 3). It preferentially binds and activates epithelial cell FGF R2 (IIIb) and interacts more weakly with FGF R1 (IIIb) (4). FGF10 plays an important role in many tissues during embryogenesis. This includes limb bud initiation (5), palate development (6), branching morphogenesis and directional outgrowth of lung buds (7, 8), formation of the otic vesicle and chochlea (9), adipogenesis (10), folliculogenesis (11), cardiomyocyte different |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P70492 |
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| Catalog # | 145700 |
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| Order / More Info | FGF-10, Recombinant, Rat, aa37-215 (KGF-2, Fibroblast Growth Factor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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