| 产品详情 |
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| Product Name | AMG-47a |
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| Description | MW: 535.56. Purity ≥98% by HPLC. Background: AMG-47a is a potent inhibitor of Lck and T cell proliferation. It exhibits anti-inflammatory activity (ED?? = 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice. In several other in vitro assays, AMG-47 displays subnanomolar inhibition against Lck, and low (<10 nM) inhibition against other hard to inhibit kinases such as KDR and SRC and MAPK alpha (p38alpha). In addition, at slightly higher doses but well under 10 uM, AMG-47 effectively i |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [4-Methyl-3-[2-[[2-(4-morpholinyl)ethyl]amino]-6-quinazolinyl]-N-[3-(trifluoromethyl)phenyl]benzamide] |
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| Gene, Accession, CAS # | CAS: 882663-88-9 |
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| Catalog # | MBS842792 |
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| Order / More Info | AMG-47a from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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