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| Product Name | a1-Microglobulin, Human, 95+% |
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| Description | Purity ≥ 95% by SDS-PAGE shows a single band consistent with a molecular weight of ~30kD. Immunological identity confirmed by Radial immunodiffusion (RID). Alpha1-microglobulin is a plasma protein synthesized in the liver. It consists of a single polypeptide chain which is synthesized from the same mRNA as bikunin, the light-chain of inter-alpha-trypsin inhibitor. Bikunin is cleaved before the secretion of alpha1-Microglobulin. Alpha1-Microglobulin is strongly associated with a yellow-brown chromophore of unknown structure and about half the plasma alpha1-Microglobulin is convalently linked to monomeric IgA. The plasma concentration range is 20-100mg/L. The function is not known. It has been implicated in immunoregulation and through its translation as a diprotein with bikunin it is associated with proteolysis inhibition. Elevated levels are associated with renal disorders and abnormalities of the renal tubules, elevated plasma IgA. Sub-normal levels are associated with HIV-infection, |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | M3890-12B |
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| Order / More Info | a1-Microglobulin, Human, 95+% from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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