| 产品详情 |
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| Product Name | Amidepsine D |
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| Description | Purity >95%. Diacylglycerol acyltransferases (DGATs) catalyze the final step in triglyceride synthesis. DGAT-1 deficient mice demonstrate a phenotype that is protective against the development of diet-induced obesity or insulin resistance, implicating the actions of this enzyme in the development of such metabolic disorders. Amidepsine D is a fungal metabolite isolated from the culture broth of Humicola sp. FO-2942 that inhibits DGAT activity (IC50 = 17.5 µM in rat liver microsomes). It inhibits triacylglycerol formation in Raji cells with an IC50 value of 2.8 µM. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[(2,4-dimethoxy-6-methylbenzoyl)oxy]-2-hydroxy-6-methyl-benzoic acid, 4-carboxy-3-hydroxy-5-methylphenyl ester |
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| Gene, Accession, CAS # | CAS: 79786-34-8 |
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| Catalog # | LS-H6505 |
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| Order / More Info | Amidepsine D from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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