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| Product Name | Resistin, Recombinant, Human |
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| Description | Purity ~90% (SDS-PAGE). Resistin (resistanceto insulin), also known as adipocytespecific secretory factor (ADSF) and found in inflammatory zone 3 (FIZZ3), is a 10kD member of a small family of secreted cysteinerich peptide hormones. These molecules purportedly play some role in inflammation, glucose metabolism, and angiogenesis (1, 2, 3, 4). Human Resistin precursor is 108 amino acids (aa) in length. It contains an 18 aa signal sequence plus a 90 aa mature region. The mature region shows an Nterminal ahelical tail (aa 23 44) and a Cterminal Bsheet globular head (aa 47 108) (5 7). The Resistin molecule circulates as either a noncovalent trimer (minor form), or a disulfidelinked homohexamer (major form). Noncovalent trimers are generated when the ahelical segments selfassociate to form a threestranded coiledcoil structure. Covalent hexamers subsequently appear when the free Cys at position #26 is engaged by adjacent trimers. It is hypothesized that the hexamer is the inactive form of the |
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| Size | 5ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Resistin, Recombinant, Human (RETN, RETN1, RSTN, Adipose Tissue-specific Secretory Factor, ADSF, C/EBP-epsilon-regulated Myeloid-specific Secreted Cysteine-rich Protein, Cysteine-rich Secreted Protein A12-alpha-like 2, Cysteine-rich Secreted Protein FIZZ3, Found in Inflammatory Zone 3, FIZZ3, HXCP1, MGC126603, MGC126609, PRO1199, UNQ407, XCP1) |
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| Gene, Accession, CAS # | SwissProt: Q9HD89 |
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| Catalog # | R1585E |
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| Order / More Info | Resistin, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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