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| Product Name | SPOP, 1-374aa, Human, His tag, E Coli |
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| Description | MW: 44.3kDa (394aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. SPOP (speckle-type POZ protein), also known as TEF2, is a member of the Tdpoz family containing one N-terminal MATH (Meprin and TRAF homology) domain and one C-terminal BTB/POZ domain. This protein inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex. Through an interaction with CuL-3, SPOP is involved in ubiquitinylation and protein degradation. Recombin |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.25 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Speckle-type POZ protein; TEF2] |
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| Gene, Accession, CAS # | SPOP, Gene ID: 8405, Accession: NP_001007231 |
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| Catalog # | MBS203829 |
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| Order / More Info | SPOP, 1-374aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Kwon J.E., et al. (2006) J. Biol. Chem. 281:12664-12672; Furukawa M., et al. (2003) Nat. Cell Biol. 5:1001-1007 |
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