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| Product Name | PDE6A, Active |
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| Description | 31-end. MW: ~120 kDa. Description: Recombinant human PDE6A (31-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: PDE6A encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A and is expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is est |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | PDE Assay |
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| Other Names | [Homo sapiens phosphodiesterase 6A (PDE6A), mRNA; Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha; phosphodiesterase 6A; PDE V-B1] |
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| Gene, Accession, CAS # | PDE6A, Gene ID: 5145, Accession: NM_000440.2 |
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| Catalog # | MBS515637 |
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| Order / More Info | PDE6A, Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Pittler, S. J. et.al: Molecular characterization of human and bovine rod photoreceptor cGMP phosphodiesterase alpha- subunit and chromosomal localization of the human gene. Genomics 6: 272-283, 1990. 2. Danciger, M. et.al: Genetic mapping demonstrates that the alpha-subunit of retinal cGMP-phosphodiesterase is not the site of the rd mutation. Exp. Eye Res. 51: 185-189, 1990. |
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