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| Product Name | PDE2A, Active, Recombinant, Human, FLAG-Tag |
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| Description | Purified (~84%). Phosphodiesterase 2A is a cGMP stimulated, cAMP/cGMP dual-specific phosphodiesterase whose hydrolytic activity is stimulated by the presence of cGMP binding to the GAF domain. PDE2A has been implicated in penile erectile dysfunction and in the regulation of fluid and inflammatory cell transit across the endothelial cell barrier (i.e., venous and capillary). PDE2A activity is inhibited by erythro-9-(2-hydroxyl-3-nonyl)adenine (EHNA). At least three isoforms have been reported (PDE2A1, PDE2A2, and PDE2A3). Source: Recombinant corresponding to aa2-941 from human PDE2A1, fused to FLAG-tag at N-terminal, expressed in a Baculovirus infected Sf9 cell expression system. Molecular Weight: ~106kD Applications: Suitable for use in the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
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| Size | 5ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PDE2A, Active, Recombinant, Human, FLAG-Tag (cGMP-dependent 3',5'-cyclic Phosphodiesterase, Cyclic GMP-stimulated Phosphodiesterase, CGS-PDE, cGSPDE) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 137332 |
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| Price | |
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| Order / More Info | PDE2A, Active, Recombinant, Human, FLAG-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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