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| Product Name | PDE5A, Active |
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| Description | 537-end. MW: ~63 kDa. Description: Recombinant human PDE5A (537-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: PDE5A is a member of the cyclic nucleotide phosphodiesterase family. PDE5A is a cGMP-specific phosphodiesterase and hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. PDE5A regulates nitri |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | PDE Assay |
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| Other Names | [Homo sapiens phosphodiesterase 5A (PDE5A), transcript variant 1, mRNA; cGMP-specific 3',5'-cyclic phosphodiesterase; cGMP-specific 3',5'-cyclic phosphodiesterase; phosphodiesterase 5A; cGMP-binding cGMP-specific phosphodiesterase; CGB-PDE] |
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| Gene, Accession, CAS # | PDE5A, Gene ID: 8654, Accession: NM_001083.3 |
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| Catalog # | MBS515635 |
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| Order / More Info | PDE5A, Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Mancina R, et al: Expression and functional activity of phosphodiesterase type 5 in human and rabbit vas deferens. Mol Hum Reprod. 2005 Feb;11 (2):107-15. 2. Pokreisz P, et al: Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice. Circulation. 2009 Jan 27;119 (3):408-16. |
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