| 产品详情 |
| Edit |   |
|---|
| Product Name | PDE10A, BioAssay™ Kit (cAMP and cAMP-inhibited cGMP 3',5'-cyclic Phosphodiesterase 10A) |
|---|
| Description | Phosphodiesterases (PDEs) play an important role in dynamic regulation of cAMP and cGMP signaling. PDE10A is a dual substrate PDE highly expressed in striatal medium spiny neurons. PDE10A inhibitors can improve the cognitive symptoms of schizophrenia, and exhibit potential therapeutic value for Huntington's Disease. The PDE10A Assay Kit is designed for identification of PDE10A inhibitors using fluorescence polarization. The assay is based on the binding of a fluorescent nucleotide monophosphate generated by PDE10A to the binding agent. Intended Use: Designed for identification of PDE10A inhibitors using fluorescence polarization. Test Principle: The PDE10A inhibitor screening assay kit comes in a convenient 96-well format, including purified PDE10A enzyme, fluorescently labeled PDE10A substrate (cAMP), binding agent, and PDE assay buffer for 100 enzyme reactions. The key to the PDE10A Assay Kit is the specific binding agent. Using this kit, only two simple steps on a microtiter plate a |
|---|
| Size | 100 tests |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 137324 |
|---|
| Price | |
|---|
| Order / More Info | PDE10A, BioAssay™ Kit (cAMP and cAMP-inhibited cGMP 3',5'-cyclic Phosphodiesterase 10A) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|