| 产品详情 |
| Edit |   |
|---|
| Product Name | Matrix Metalloproteinase-13, Recombinant, Human (MMP-13, Collagenase-3) |
|---|
| Description | Purity ~90% (SDS-PAGE). Latent recombinant human pro-collagenase (MMP-13) also called collagenase-3 truncated from C-terminal. Matrix Metalloproteinase-13 (MMP-13) is an enzyme that is a member of the MMP extracellular protease family. Extracellular protease enzymes, by virtue of their broad substrate specificities, play a role in both normal and disease states of tissue proliferation. Among the targets of MMP-13 are collagen, gelatin, entactin, pro-TNF-a, and chemokine SDF-11-4. MMP-13 is found in its latent form as a 52-56kD glycosylated proenzyme. Upon cleavage the 22-46kD MMP-1 becomes active in extracellular matrix remodeling. Because of the prominent role that MMP-1 plays in cell migration and metastasis, it is an important target for inhibition screening. Source: Recombinant protein corresponding to human MMP-13, a single, non-glycosylated, polypeptide chain, expressed in E. coli. Molecular Weight: ~27kD Biological Activity: Determined by the cleavage of fluorogenic peptide, 100 |
|---|
| Size | 1ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 209086 |
|---|
| Price | |
|---|
| Order / More Info | Matrix Metalloproteinase-13, Recombinant, Human (MMP-13, Collagenase-3) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|