| 产品详情 |
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| Product Name | HDAC Inhibitor XVII |
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| Description | Purity ~99% (HPLC). A cell-permeable N-hydroxycinnamide derivative that acts a highly potent and HDAC8-selective histone deacetylase inhibitor (IC50 = 27nM), displaying much reduced or little potency against HDAC1/3 (IC50 = 3.0uM), HDAC2/4/6/10/11 (IC50 >20uM), or total HDAC activity in HeLa nuclear extract (IC50 >10uM). Reported to preferentially inhibit the proliferation of human lung cancer cells CL1-5, H1299, and A549 (IC50 from 7 to 8uM), while being much less toxic to normal human lung IMR-90 cells (73% inhibition at 40uM). Primary Target: HDAC8 selective Primary Target IC50: 27nM Molar Mass: 345.39 Solubility: DMSO |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HDAC Inhibitor XVII ((E)-N-Hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamide, Histone Deacetylase Inhibitor XVII) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217413 |
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| Price | |
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| Order / More Info | HDAC Inhibitor XVII from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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