产品详情 |
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Antigenic Specificity | Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) |
Clone | 3B1E9 |
Host Species | Mouse |
Reactive Species | human, porcine, cow, goat, fish |
Isotype | IgG2a,kappa |
Format | Protein A purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA,Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. It catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Besides its functioning as a glycolytic enzyme in cytoplasm, recent evidence suggest that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of findings appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age-related neuronal diseases, such as Alzheimers and Huntingtons disease. GAPDH Antibody, mAb, Mouse is produced from the hybridoma resulting from fusion of Sp2/0 myeloma and lymphocytes obtained from mouse immunized with human GAPDH protein from erythrocytes. |
Immunogen | Human GAPDH protein from erythrocytes |
Other Names | CG8893|Dmel\\CG8893|GA3PDH|GADPH|GAP|GAPDH|GAPDH II|GAPDH2|Gapd|Gapdh|Gapdh-2|Gapdh13F|GAPD|g3pd|gapd|GB14798|GAPC-2|GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE C-2|T6J4.17|T6J4_17|glyceraldehyde-3-phosphate dehydrogenase C2|BEST:GH12586|CG12055|Dmel\\CG12055|GAPDH I|GAPDH-1|GAPDH1|GAPDHI|Gapdh-1|Gapdh43E|gadph|gapdh|gapdh-1|gh12586|KNC-NDS6|G3PD|cb609|mg:bb02e05|wu:fb33a10|wu:ft80f05|G3PDH |
Gene, Accession # | Gene ID: 2597,396823,786101,100860872 |
Catalog # | ABIN2017607 |
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Order / More Info | Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 22507201, 22659571, 23349096, 23541532, 25410857 |
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