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| Product Name | BCL10, Recombinant, Human, aa1-233, His-Tag (B-cell lymphoma/leukemia 10) |
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| Description | Purity ~85% (SDS-PAGE). BCL10, also known as B-cell lymphoma/leukemia 10, contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. It is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Source: Recombinant protein corresponding to aa1-233 of human BCL10, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~28.8kD AA |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_003912 |
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| Catalog # | 349718 |
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| Order / More Info | BCL10, Recombinant, Human, aa1-233, His-Tag (B-cell lymphoma/leukemia 10) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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