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| Product Name | BCL2, Recombinant, Human, His-Tag (Apoptosis Regulator Bcl-2, B Cell CLL/Lymphoma 2, Bcl-2) |
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| Description | Purity ~90% (SDS-PAGE). Bcl-2, also known as B-cell lymphoma protein 2 alpha, is an anti-apoptotic protein located primarily in the outer mitochondrial membrane that blocks the apoptotic death of some cells such as lymphocytes. BCL-2 is thought to regulate cell death by controlling the mitochondrial membrane permeability during apotosis. Bcl-2 exerts its anti-apoptotic function through inhibiting caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). The Bcl-2 gene has been related with a number of cancers, including melanoma, breast, prostate, and lung carcinomas, as well as schizophrenia and autoimmunity. Recombinant Bcl-2 protein was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Source: Recombinant protein corresponding to aa1-211, from human Bcl2, expressed in E.coli. Molecular Weight: ~25.4kD ( |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 137559 |
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| Order / More Info | BCL2, Recombinant, Human, His-Tag (Apoptosis Regulator Bcl-2, B Cell CLL/Lymphoma 2, Bcl-2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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