| 产品详情 |
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| Product Name | GPR40 Agonist II |
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| Description | Purity ~98% (HPLC). A cell-permeable alkynedihydrocinnamic acid that acts as a potent GPR40/FFA1 agonist (EC50=40.7nM in inducing Ca2+ mobilization in hFFA1-expressing 1321N1 cells) with >100-fold selectivity over GPR43/FFA2, GPR41/FFA3, and a panel of 56 other receptors, ion channels, and transporters. Reported to enhance 12mM glucose-induced insulin secretion from rat INS-1E B-cells (by 34% at 10uM) and exhibit good aqueous solubility (199uM in PBS at pH 7.4), as well as chemical and metabolic stability. Formula: C16H11Cl2NO2 Molecular Weight: 320.2 Solubility: DMSO |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | GPR40 Agonist II (FFA1 Agonist II, Free Fatty Acid Receptor 1 Agonist II, 3-(4-((2,6-Dichloropyridin-4-yl)ethynyl)phenyl)propanoic Acid) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217393 |
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| Price | |
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| Order / More Info | GPR40 Agonist II from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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