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| Product Name | GPR119 Agonist, AS1269574 |
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| Description | Purity ~99% (HPLC). A pyrimidine compound that acts as an effective GPR119 agonist (EC50=2.5uM in stimulating cAMP in hGPR119-expressing HEK293 cells) and reportedly exhibits no activity toward B-adrenergic or GLP-1 receptors. Shown to enhance 16.8mM glucose-induced insulin secretion from murine MIN-6 B-cells (mU/20 min=0.44 and 0.22, respectively, with or without 10uM AS1269574) in vitro and improve glucose tolerance in normal mice (100mg/kg; p.o.) without any significant hypoglycemic effect in vivo. Formula: C13H14BrN3O Solubility: DMSO Molecular Weight: 308.2 |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | GPR119 Agonist, AS1269574 (G-Protein Coupled Receptor 119 Agonist, 2-((2-(4-Bromophenyl)-6-methylpyrimidin-4-yl)amino)ethanol, GPCR2 Agonist, MGC119957 Agonist, SNORF25 Agonist) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217392 |
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| Order / More Info | GPR119 Agonist, AS1269574 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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