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| Product Name | GPR109b Agonist (1-(iso-Propyl)-1H-benzotriazole-5-carboxylic Acid) |
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| Description | Purity ~98% (HPLC). A cell-permeable Niacin triazolo derivative that acts as a potent and selective agonist toward the human orphan G-protein-coupled receptor GPR109b/HM74, but not GPR109a/HM74A or b-adrenergic receptor. Effectively inhibits cAMP elevation induced by forskolin (5uM) and isoproterenol (1uM), respectively, in GPR109b-expressing CHO cells (EC50=400nM) and freshly isolated human adipocytes (EC50 about 1uM). Formula: C10H11N3O2 Solubility: DMSO (50mg/ml), Ethanol (2mg/ml) Molecular Weight: 205.2 |
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| Size | 25mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217391 |
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| Order / More Info | GPR109b Agonist (1-(iso-Propyl)-1H-benzotriazole-5-carboxylic Acid) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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