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| Product Name | PARK7, Recombinant, Human, aa1-188, GST-Tag (Protein DJ-1) |
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| Description | Purity ~90% (SDS-PAGE). Protein deglycase that repairs methylglyoxal- and glyoxal-glycated amino acids and proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteines, arginines and lysines residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hithioacetals and aminocarbinols), preventing the formation of advanced glycation endproducts (AGE). Plays an important role in cell protection against oxidative stress and cell death acting as oxidative stress sensor and redox-sensitive chaperone and protease; functions probably related to its primary function. It is involved in neuroprotective mechanisms like the stabilization of NFE2L2 and PINK1 proteins, male fertility as a positive regulator of androgen signaling pathway as well as cell growth and transformation through, for instance, the modulation of NF-kappa-B signaling pathway. Its involvent in protein repair could also explain other unrelate |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Oncogene DJ1, Parkinson disease protein 7 |
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| Gene, Accession, CAS # | SwissProt: Q99497 |
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| Catalog # | 374616 |
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| Order / More Info | PARK7, Recombinant, Human, aa1-188, GST-Tag (Protein DJ-1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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