| 产品详情 |
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| Antigenic Specificity | CD276 Molecule (CD276) |
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| Clone | 6A1 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ELISA,Flow Cytometry (FACS),Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Costimulatory B7Molecules (e.g., B7-1, or CD80, MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558). May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling. |
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| Immunogen | Purified recombinant fragment of human CD276 expressed in E. coli. |
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| Other Names | sc:d0645|zgc:158279|6030411F23Rik|AU016588|B7RP-2|B7h3|B7H3|4Ig-B7-H3|B7-H3 |
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| Gene, Accession # | Gene ID: 80381 |
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| Catalog # | ABIN969018 |
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| Price | |
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| Order / More Info | CD276 Molecule (CD276) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 15489334, 16274630 |
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