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| Product Name | SEPX1, Recombinant, Human, aa1-116, His-tag |
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| Description | Purity ~90% (SDS-PAGE). SEPX1, also known as Methionine sulfoxide reductase B1 (MSRB1), is a selenoprotein. Methionine sulfoxide reductases(MSRs) catalyze reduction of free and protein-bound methionine sulfoxides to corresponding methionines. The oxidation of methionine by ROS generates a diastereomeric mixture of methionine-S-sulfoxide (Met-S-SO) and methionine-R-sulfoxide (Met-R-SO). Two distinct enzyme families evolved for reduction of these sulfoxides, with methionine-S-sulfoxide reductase (MsrA) being stereospecific for Met-S-SO and methionine-R- sulfoxide reductase (MsrB) for Met-R-SO. In bacteria, the selenocystein (Sec/U) element is located immediately following the UGA codon within the reading frame for the selenoprotein so we mutated Sec-95 to Cys. Source: Recombinant protein corresponding to aa1-116 from human SEPX1, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~14.8kD (136aa) AA |
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| Size | 50ug, 250ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SEPX1, Recombinant, Human, aa1-116, His-Tag (Methionine-R-sulfoxide reductase B1, Selenoprotein X, HSPC270, MSRB1, SELR, SELX, MSRB1) |
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| Gene, Accession, CAS # | Accession: NP_057416 |
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| Catalog # | 351493 |
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| Order / More Info | SEPX1, Recombinant, Human, aa1-116, His-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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