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| Product Name | TNFAIP3, Recombinant, Human, FLAG-Tag |
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| Description | Purified (~10%). Tumor necrosis factor, alpha-induced protein 3 (TNFAIP3) is a de-ubiquitinating enzyme that contains an N- terminal catalytic domain belonging to the ovarian-tumor superfamily of cysteine proteases (1). TNFAIP3 suppresses apoptosis.It is expressed in various cell types in response to a variety of stimuli that activate the transcription factor NF- kB, including Il-1, CD40 ligand, and PMA (3). TNFAIP3 has been strongly suggested as a key protein involved in tamoxifen resistance, and thus represents both a new breast cancer marker and a promising target for developing new strategies to prevent the emergence of acquired mechanisms of drug resistance in breast cancer (2). Source: Recombinant corresponding to aa2-791 from human TNFAIP3, fused to FLAG-tag at N-terminal, expressedin Sf9 insect cells via a baculovirus expression system. Molecular Weight: ~90.5kD Applications: Suitable for for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TNFAIP3, Recombinant, Human, FLAG-Tag (Tumor Necrosis Factor Alpha-induced Protein 3, TNF Alpha-induced Protein 3, OTU Domain-containing Protein 7C, Putative DNA-binding Protein A20, Zinc Finger Protein A20, OTUD7C) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 137384 |
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| Order / More Info | TNFAIP3, Recombinant, Human, FLAG-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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