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| Product Name | DPS, Recombinant, Heliocobacter Pylori, aa1-144, His-SUMO-Tag (DNA Protection During Starvation Protein) |
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| Description | Purity ~85% (SDS-PAGE). Protects DNA from oxidative damage by sequestering intracellular Fe2+ ion and storing it in the form of Fe3+ oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe2+ ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity). Required for the survival in the presence of oxidative stress. Dps is also a virulence factor that activates neutrophils, mast cells and monocytes. It binds to neutrophil-glycosphingolipids and to sulfated carbohydrates on mucin. It might have a role in the accumulation of neutrophils and monocytes at the site of infection. Induces superoxide anion generation, adhesion and chemotaxis of neutrophils, through a pertussis toxin-sensitive pathway involving MAP kinases. Source: Recombinant protein corresponding to aa1-144 from Heliocobacter pylori DNA protection during starvation protein, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. AA |
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| Size | 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P43313 |
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| Catalog # | 370592 |
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| Order / More Info | DPS, Recombinant, Heliocobacter Pylori, aa1-144, His-SUMO-Tag (DNA Protection During Starvation Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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