| 产品详情 |
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| Antigenic Specificity | CD86 Molecule (CD86) |
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| Clone | GL-1 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a |
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| Format | Protein G purified |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry (ICC),Functional Studies (Func),Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunoprecipitation (IP),Flow Cytometry (FACS) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet, there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response. |
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| Immunogen | LPS-activated CBA/Cs mouse splenic B cells |
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| Other Names | B7-2|B7|B7.2|B70|CLS1|Cd28l2|ETC-1|Ly-58|Ly58|MB7|MB7-2|TS/A-2|CD28LG2|LAB72 |
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| Gene, Accession # | Gene ID: 12524 |
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| Catalog # | ABIN457401 |
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| Price | |
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| Order / More Info | CD86 Molecule (CD86) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 12902475, 10499913, 11049981, 18184859, 7694361, 19672303, 17989345, 15677501 |
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