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| Product Name | DR1, aa1-176, Recombinant, Human (Down-regulator of transcription 1, TBP-binding) |
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| Description | Purity ~85% (SDS-PAGE). DR1, also known as NC2-beta, is a TBP (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. By selectively repressing polymerases II and III, DR1 may shift the physiological balance of transcriptional output in favor of polymerase I. Source: Recombinant corresponding to aa1-176 of human recombinant DR1 protein, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MASSSGNDDD LTIPRAAINK MIKETLPNVR VANDARELVV NCCTEFIHLI SSEANEICNK SEKKTISPEH VIQALESLGF GSYISEVKEV LQECKTVALK RRKASSRLEN LGIPEEELLR QQQELFAKAR QQQAELAQQE WLQMQQAAQQ AQLAAASASA SNQAGSSQDE EDDDDI |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_001929 |
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| Catalog # | D9070-04 |
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| Order / More Info | DR1, aa1-176, Recombinant, Human (Down-regulator of transcription 1, TBP-binding) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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