| 产品详情 |
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| Product Name | 2',3'-Dideoxyadenosine 5'-triphosphate |
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| Description | Purity >99%. 2',3'-Dideoxyadenosine 5'-triphosphate (ddATP) is an in vitro inhibitor of reverse transcriptases from retroviruses, including HIV-1 and visna (Ki s = 20 and 37 nM, respectively). It also blocks, in vitro, mammalian and bacterial DNA polymerases. ddATP, produced intracellularly by the phosphorylation of exogenously supplied 2',3'-dideoxyadenosine, competes with dATP, resulting in chain termination. Because of this activity, dideoxynucleoside 5'-triphosphates, including ddATP, are used to terminate chain extension produced by the Taq polymerase used in polymerase chain reactions. It is also an antagonist of the purinergic receptor P2X2/3 (pIC50 = 6.5). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2',3'-dideoxy-adenosine 5'-(tetrahydrogen triphosphate), ddATP |
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| Gene, Accession, CAS # | CAS: 24027-80-3 |
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| Catalog # | LS-H5931 |
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| Price | |
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| Order / More Info | 2',3'-Dideoxyadenosine 5'-triphosphate from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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