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| Product Name | TESC, Recombinant, Human, aa2-214, His-SUMO-Tag (Tescalcin) |
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| Description | Purity ~90% (SDS-PAGE). Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin. Source: Recombinant protein corresponding to aa2-214 from human TESC, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~40.6kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Tescalcin, TSC |
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| Gene, Accession, CAS # | SwissProt: Q96BS2 |
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| Catalog # | 375526 |
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| Order / More Info | TESC, Recombinant, Human, aa2-214, His-SUMO-Tag (Tescalcin) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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